Whereas very low-count MBL not often progresses to CLL, high-rely MBL progresses to CLL demanding therapy at a amount of one% to 2% a year. Substantial-rely MBL is distinguished from Rai 0 CLL depending on whether the B-mobile depend is over or beneath five × 109/L. Whilst individuals with both significant-count MBL and CLL Rai stage 0 are at incr